trans-3-hydroxy-L-proline
TL;DR: trans-3-hydroxy-L-proline (CAS 618-28-0) is a chemical compound with molecular formula C5H9NO3 and molecular weight 131.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid
Also Known As: trans-3-hydroxy-L-proline, (2S,3S)-3-Hydroxypyrrolidine-2-carboxylic acid, (3S)-3-hydroxy-L-proline, 3-Hydroxyproline, trans-3-Hydroxyproline
| Molecular Formula | C5H9NO3 |
|---|---|
| Molecular Weight | 131.06 g/mol |
| LogP | -3.2 |
| Topological Polar Surface Area | 69.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 131.05824 |
| Heavy Atoms | 9 |
| Complexity | 125.0 |
Chemical Identifiers
| CAS Number | 618-28-0 |
|---|---|
| SMILES | C1CN[C@@H]([C@H]1O)C(=O)O |
| InChIKey | BJBUEDPLEOHJGE-IMJSIDKUSA-N |
Patent-Derived Application Labels
Derived from 11 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
trans-3-hydroxy-L-proline (CAS 618-28-0), with molecular formula C5H9NO3 and molecular weight 131.06 g/mol. IUPAC: (2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid.
Chemical Property Profile of trans-3-hydroxy-L-proline
Property Insights of trans-3-hydroxy-L-proline
The XLogP value of -3.2 indicates that trans-3-hydroxy-L-proline is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 69.6 Ų falls within the moderate polarity range, balancing permeability and solubility for trans-3-hydroxy-L-proline. Following Lipinski's Rule of Five, trans-3-hydroxy-L-proline has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of trans-3-hydroxy-L-proline?
The CAS number of trans-3-hydroxy-L-proline is 618-28-0.
What is the molecular formula of trans-3-hydroxy-L-proline?
The molecular formula of trans-3-hydroxy-L-proline is C5H9NO3.
What is the molecular weight of trans-3-hydroxy-L-proline?
The molecular weight of trans-3-hydroxy-L-proline is 131.06 g/mol.
Where can I buy trans-3-hydroxy-L-proline?
You can request a quote for trans-3-hydroxy-L-proline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for trans-3-hydroxy-L-proline?
Yes, KEHONG BIO provides custom synthesis services for trans-3-hydroxy-L-proline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.