Azaftozine
TL;DR: Azaftozine (CAS 6160-69-6) is a chemical compound with molecular formula C23H24F3N3OS and molecular weight 447.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-1-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-one
Also Known As: Azaftozine, Azaftozina, Azaftozinum, Nonaftazin, Azaftozine [INN]
| Molecular Formula | C23H24F3N3OS |
|---|---|
| Molecular Weight | 447.16 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 52.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 447.1592 |
| Heavy Atoms | 31 |
| Complexity | 662.0 |
Chemical Identifiers
| CAS Number | 6160-69-6 |
|---|---|
| SMILES | C1CC2CN(CCN2C1)CCC(=O)N3C4=CC=CC=C4SC5=C3C=C(C=C5)C(F)(F)F |
| InChIKey | HOZLLXONNGPAPJ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Azaftozine (CAS 6160-69-6), with molecular formula C23H24F3N3OS and molecular weight 447.16 g/mol. IUPAC: 3-(3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-1-[2-(trifluoromethyl)phenothiazin-10-yl]propan-1-one.
Chemical Property Profile of Azaftozine
Property Insights of Azaftozine
The XLogP value of 4.2 indicates that Azaftozine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.1 Ų, Azaftozine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Azaftozine has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Azaftozine?
The CAS number of Azaftozine is 6160-69-6.
What is the molecular formula of Azaftozine?
The molecular formula of Azaftozine is C23H24F3N3OS.
What is the molecular weight of Azaftozine?
The molecular weight of Azaftozine is 447.16 g/mol.
Where can I buy Azaftozine?
You can request a quote for Azaftozine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Azaftozine?
Yes, KEHONG BIO provides custom synthesis services for Azaftozine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.