1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one
概要：1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one（CAS 615276-21-6）是一种化学化合物，分子式为C23H20N2O3S，分子量为404.12 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methylphenyl)methylidene]-5-phenylpyrrolidine-2,3-dione
又称：1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one, (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy(4-methylphenyl)methylidene]-5-phenylpyrrolidine-2,3-dione, (4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methylphenyl)methylidene]-5-phenylpyrrolidine-2,3-dione, 1-(4,5-dimethyl(1,3-thiazol-2-yl))-3-hydroxy-4-[(4-methylphenyl)carbonyl]-5-ph enyl-3-pyrrolin-2-one
| 分子式 | C23H20N2O3S |
|---|---|
| 分子量 | 404.12 g/mol |
| LogP | 4.69466 |
| 拓扑极性表面积 | 70.5 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 5 |
| 可旋转键数 | 3 |
| 精确质量 | 404.11948 |
| 重原子数 | 29 |
| 复杂度 | 1111.1895 |
化学标识符
| CAS 编号 | 615276-21-6 |
|---|---|
| SMILES | CC1=CC=C(C=C1)/C(=C\2/C(N(C(=O)C2=O)C3=NC(=C(S3)C)C)C4=CC=CC=C4)/O |
产品概述
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one（CAS 615276-21-6），分子式为C23H20N2O3S，分子量为404.12 g/mol。IUPAC名：(4E)-1-(4,5-dimethyl-1,3-thiazol-2-yl)-4-[hydroxy-(4-methylphenyl)methylidene]-5-phenylpyrrolidine-2,3-dione。
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one化学性质概览
属性洞察：1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one的XLogP值为4.69466，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为70.5 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one有1个氢键供体和5个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one的CAS号是多少？
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one的CAS号为615276-21-6。
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one的分子式是什么？
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one的分子式为C23H20N2O3S。
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one的分子量是多少？
1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one的分子量为404.12 g/mol。
在哪里可以购买1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one？
您可以直接向科弘生物询价1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one的定制合成服务？
是的，科弘生物提供1-(4,5-dimethylthiazol-2-yl)-3-hydroxy-4-(4-methylbenzoyl)-5-phenyl-1H-pyrrol-2(5H)-one及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。