2'-Deoxy-2'-(trifluoromethyl)uridine
TL;DR: 2'-Deoxy-2'-(trifluoromethyl)uridine (CAS 614735-32-9) is a chemical compound with molecular formula C10H11F3N2O5 and molecular weight 296.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-(trifluoromethyl)oxolan-2-yl]pyrimidine-2,4-dione
Also Known As: 2'-Deoxy-2'-(trifluoromethyl)uridine, J1.927.888C, 1-[2-(Trifluoromethyl)-2-deoxy-beta-D-ribofuranosyl]-4-hydroxypyrimidine-2(1H)-one, 1-((2R,3R,4S,5R)-4-Hydroxy-5-hydroxymethyl-3-trifluoromethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione, 1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-(trifluoromethyl)oxolan-2-yl]pyrimidine-2,4-dione
| Molecular Formula | C10H11F3N2O5 |
|---|---|
| Molecular Weight | 296.06 g/mol |
| LogP | -0.6 |
| Topological Polar Surface Area | 99.1 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 296.062 |
| Heavy Atoms | 20 |
| Complexity | 453.0 |
Chemical Identifiers
| CAS Number | 614735-32-9 |
|---|---|
| SMILES | C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)C(F)(F)F |
| InChIKey | AKXNGNCUONECRN-XVFCMESISA-N |
Product Overview
2'-Deoxy-2'-(trifluoromethyl)uridine (CAS 614735-32-9), with molecular formula C10H11F3N2O5 and molecular weight 296.06 g/mol. IUPAC: 1-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-(trifluoromethyl)oxolan-2-yl]pyrimidine-2,4-dione.
Chemical Property Profile of 2'-Deoxy-2'-(trifluoromethyl)uridine
Property Insights of 2'-Deoxy-2'-(trifluoromethyl)uridine
The XLogP value of -0.6 indicates that 2'-Deoxy-2'-(trifluoromethyl)uridine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-Deoxy-2'-(trifluoromethyl)uridine. Following Lipinski's Rule of Five, 2'-Deoxy-2'-(trifluoromethyl)uridine has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Deoxy-2'-(trifluoromethyl)uridine?
The CAS number of 2'-Deoxy-2'-(trifluoromethyl)uridine is 614735-32-9.
What is the molecular formula of 2'-Deoxy-2'-(trifluoromethyl)uridine?
The molecular formula of 2'-Deoxy-2'-(trifluoromethyl)uridine is C10H11F3N2O5.
What is the molecular weight of 2'-Deoxy-2'-(trifluoromethyl)uridine?
The molecular weight of 2'-Deoxy-2'-(trifluoromethyl)uridine is 296.06 g/mol.
Where can I buy 2'-Deoxy-2'-(trifluoromethyl)uridine?
You can request a quote for 2'-Deoxy-2'-(trifluoromethyl)uridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Deoxy-2'-(trifluoromethyl)uridine?
Yes, KEHONG BIO provides custom synthesis services for 2'-Deoxy-2'-(trifluoromethyl)uridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.