2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one
TL;DR: 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one (CAS 6145-05-7) is a chemical compound with molecular formula C21H18N2O and molecular weight 314.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one
Also Known As: BIM-0005897.P001, 2-(4-methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one, J2.879.150J, 2,3-dihydro-3-phenyl-2-p-tolylquinazolin-4(1h)-one, 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazoline-4(3H)-one
| Molecular Formula | C21H18N2O |
|---|---|
| Molecular Weight | 314.14 g/mol |
| LogP | 4.76612 |
| Topological Polar Surface Area | 32.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 314.1419 |
| Heavy Atoms | 24 |
| Complexity | 871.8553 |
Chemical Identifiers
| CAS Number | 6145-05-7 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2NC3=CC=CC=C3C(=O)N2C4=CC=CC=C4 |
Product Overview
2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one (CAS 6145-05-7), with molecular formula C21H18N2O and molecular weight 314.14 g/mol. IUPAC: 2-(4-methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one.
Chemical Property Profile of 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one
Property Insights of 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one
The XLogP value of 4.76612 indicates that 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.34 Ų, 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one?
The CAS number of 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one is 6145-05-7.
What is the molecular formula of 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one?
The molecular formula of 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one is C21H18N2O.
What is the molecular weight of 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one?
The molecular weight of 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one is 314.14 g/mol.
Where can I buy 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one?
You can request a quote for 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-Methylphenyl)-3-phenyl-1,2-dihydroquinazolin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.