Pyroglutamyl-histidyl-3-methylprolinamide
TL;DR: Pyroglutamyl-histidyl-3-methylprolinamide (CAS 61406-69-7) is a chemical compound with molecular formula C17H24N6O4 and molecular weight 376.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-3-(4H-imidazol-4-yl)-1-[[(2S,3S)-3-methylpyrrolidine-2-carbonyl]amino]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Also Known As: Pyr-his-3-mep-NH2, Pyr-his-3-mepro-NH2, Pyroglutamyl-histidyl-3-methylprolinamide, Pyroglutamyl-histidyl-methylprolinamide(3), (2S)-N-[(2S)-3-(4H-imidazol-4-yl)-1-[[(2S,3S)-3-methylpyrrolidine-2-carbonyl]amino]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
| Molecular Formula | C17H24N6O4 |
|---|---|
| Molecular Weight | 376.19 g/mol |
| LogP | -1.6 |
| Topological Polar Surface Area | 141.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 376.1859 |
| Heavy Atoms | 27 |
| Complexity | 691.0 |
Chemical Identifiers
| CAS Number | 61406-69-7 |
|---|---|
| SMILES | C[C@H]1CCN[C@@H]1C(=O)NC(=O)[C@H](CC2C=NC=N2)NC(=O)[C@@H]3CCC(=O)N3 |
| InChIKey | YRANAJWOIWUDMB-QJMVCYGNSA-N |
Product Overview
Pyroglutamyl-histidyl-3-methylprolinamide (CAS 61406-69-7), with molecular formula C17H24N6O4 and molecular weight 376.19 g/mol. IUPAC: (2S)-N-[(2S)-3-(4H-imidazol-4-yl)-1-[[(2S,3S)-3-methylpyrrolidine-2-carbonyl]amino]-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of Pyroglutamyl-histidyl-3-methylprolinamide
Property Insights of Pyroglutamyl-histidyl-3-methylprolinamide
The XLogP value of -1.6 indicates that Pyroglutamyl-histidyl-3-methylprolinamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 141.0 Ų indicates high polarity, suggesting Pyroglutamyl-histidyl-3-methylprolinamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Pyroglutamyl-histidyl-3-methylprolinamide has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Pyroglutamyl-histidyl-3-methylprolinamide?
The CAS number of Pyroglutamyl-histidyl-3-methylprolinamide is 61406-69-7.
What is the molecular formula of Pyroglutamyl-histidyl-3-methylprolinamide?
The molecular formula of Pyroglutamyl-histidyl-3-methylprolinamide is C17H24N6O4.
What is the molecular weight of Pyroglutamyl-histidyl-3-methylprolinamide?
The molecular weight of Pyroglutamyl-histidyl-3-methylprolinamide is 376.19 g/mol.
Where can I buy Pyroglutamyl-histidyl-3-methylprolinamide?
You can request a quote for Pyroglutamyl-histidyl-3-methylprolinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Pyroglutamyl-histidyl-3-methylprolinamide?
Yes, KEHONG BIO provides custom synthesis services for Pyroglutamyl-histidyl-3-methylprolinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.