洛芬太尼
TL;DR: 洛芬太尼 (CAS 61380-40-3) is a chemical compound with molecular formula C25H32N2O3 and molecular weight 408.24 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
洛芬太尼
methyl (3S,4R)-3-methyl-1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
Also Known As: Lofentanil, Lofentanilum, Lofentanila, lofentanyl, Lofentanilo
| Molecular Formula | C25H32N2O3 |
|---|---|
| Molecular Weight | 408.24 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 49.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 408.2413 |
| Heavy Atoms | 30 |
| Complexity | 569.0 |
Chemical Identifiers
| CAS Number | 61380-40-3 |
|---|---|
| SMILES | CCC(=O)N(C1=CC=CC=C1)[C@@]2(CCN(C[C@@H]2C)CCC3=CC=CC=C3)C(=O)OC |
| InChIKey | IMYHGORQCPYVBZ-NBGIEHNGSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
洛芬太尼 (CAS 61380-40-3), with molecular formula C25H32N2O3 and molecular weight 408.24 g/mol. IUPAC: methyl (3S,4R)-3-methyl-1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxylate.
Chemical Property Profile of 洛芬太尼
Property Insights of 洛芬太尼
The XLogP value of 4.2 indicates that 洛芬太尼 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.9 Ų, 洛芬太尼 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 洛芬太尼 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 洛芬太尼?
The CAS number of 洛芬太尼 is 61380-40-3.
What is the molecular formula of 洛芬太尼?
The molecular formula of 洛芬太尼 is C25H32N2O3.
What is the molecular weight of 洛芬太尼?
The molecular weight of 洛芬太尼 is 408.24 g/mol.
Where can I buy 洛芬太尼?
You can request a quote for 洛芬太尼 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 洛芬太尼?
Yes, KEHONG BIO provides custom synthesis services for 洛芬太尼 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.