Liothyronine hydrochloride
TL;DR: Liothyronine hydrochloride (CAS 6138-47-2) is a chemical compound with molecular formula C15H13ClI3NO4 and molecular weight 686.77 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid;hydrochloride
Also Known As: Liothyronine hydrochloride, Liothyronine HCl, trionine, liothyronine, Lyothyronin
| Molecular Formula | C15H13ClI3NO4 |
|---|---|
| Molecular Weight | 686.77 g/mol |
| LogP | 4.37 |
| Topological Polar Surface Area | 92.8 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 686.7667 |
| Heavy Atoms | 24 |
| Complexity | 402.0 |
Chemical Identifiers
| CAS Number | 6138-47-2 |
|---|---|
| SMILES | C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O.Cl |
| InChIKey | HFEMPWKWYHWPQX-YDALLXLXSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Liothyronine hydrochloride (CAS 6138-47-2), with molecular formula C15H13ClI3NO4 and molecular weight 686.77 g/mol. IUPAC: (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid;hydrochloride.
Chemical Property Profile of Liothyronine hydrochloride
Property Insights of Liothyronine hydrochloride
The XLogP value of 4.37 indicates that Liothyronine hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 92.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Liothyronine hydrochloride. Following Lipinski's Rule of Five, Liothyronine hydrochloride has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Liothyronine hydrochloride?
The CAS number of Liothyronine hydrochloride is 6138-47-2.
What is the molecular formula of Liothyronine hydrochloride?
The molecular formula of Liothyronine hydrochloride is C15H13ClI3NO4.
What is the molecular weight of Liothyronine hydrochloride?
The molecular weight of Liothyronine hydrochloride is 686.77 g/mol.
Where can I buy Liothyronine hydrochloride?
You can request a quote for Liothyronine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Liothyronine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Liothyronine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.