clobetasol
TL;DR: clobetasol (CAS 61319-46-8) is a chemical compound with molecular formula C22H28ClFO4 and molecular weight 410.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Also Known As: clobetasol, 16-epi-Clobetasol, 17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, 21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
| Molecular Formula | C22H28ClFO4 |
|---|---|
| Molecular Weight | 410.17 g/mol |
| LogP | 3.1422 |
| Topological Polar Surface Area | 74.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 410.16602 |
| Heavy Atoms | 28 |
| Complexity | 808.35846 |
Chemical Identifiers
| CAS Number | 61319-46-8 |
|---|---|
| SMILES | CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C |
Product Overview
clobetasol (CAS 61319-46-8), with molecular formula C22H28ClFO4 and molecular weight 410.17 g/mol. IUPAC: 17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.
Chemical Property Profile of clobetasol
Property Insights of clobetasol
The XLogP value of 3.1422 indicates that clobetasol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 74.6 Ų falls within the moderate polarity range, balancing permeability and solubility for clobetasol. Following Lipinski's Rule of Five, clobetasol has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of clobetasol?
The CAS number of clobetasol is 61319-46-8.
What is the molecular formula of clobetasol?
The molecular formula of clobetasol is C22H28ClFO4.
What is the molecular weight of clobetasol?
The molecular weight of clobetasol is 410.17 g/mol.
Where can I buy clobetasol?
You can request a quote for clobetasol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for clobetasol?
Yes, KEHONG BIO provides custom synthesis services for clobetasol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.