(E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide structure

(E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide

TL;DR: (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 612827-75-5) is a chemical compound with molecular formula C22H18BrN5O2S2 and molecular weight 527.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(E)-(5-bromothiophen-2-yl)methylideneamino]-2-[[4-(4-methoxyphenyl)-5-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide

Also Known As: (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide, N'-[(E)-(5-bromothiophen-2-yl)methylidene]-2-{[4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetohydrazide, N-[(1E)-2-(5-bromo(2-thienyl))-1-azavinyl]-2-[4-(4-methoxyphenyl)-5-phenyl(1,2 ,4-triazol-3-ylthio)]acetamide, N-[(E)-(5-bromothiophen-2-yl)methylideneamino]-2-[[4-(4-methoxyphenyl)-5-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS: 612827-75-5
Molecular Formula C22H18BrN5O2S2
Molecular Weight 527.01 g/mol
LogP 5.0093
Topological Polar Surface Area 81.4 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 8
Exact Mass 527.00854
Heavy Atoms 32
Complexity 1222.8693

Chemical Identifiers

CAS Number 612827-75-5
SMILES COC1=CC=C(C=C1)N2C(=NN=C2SCC(=O)N/N=C/C3=CC=C(S3)Br)C4=CC=CC=C4

Product Overview

(E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 612827-75-5), with molecular formula C22H18BrN5O2S2 and molecular weight 527.01 g/mol. IUPAC: N-[(E)-(5-bromothiophen-2-yl)methylideneamino]-2-[[4-(4-methoxyphenyl)-5-phenyl-1,2,4-triazol-3-yl]sulfanyl]acetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide

XLogP
5.0093
TPSA (Topological Polar Surface Area)
81.4
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
8
Heavy Atoms
32
Complexity
1222.8693
Exact Mass
527.00854
Monoisotopic Mass
527.00854
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide

The XLogP value of 5.0093 indicates that (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.4 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide. Following Lipinski's Rule of Five, (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide?

The CAS number of (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide is 612827-75-5.

What is the molecular formula of (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide?

The molecular formula of (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide is C22H18BrN5O2S2.

What is the molecular weight of (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide?

The molecular weight of (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide is 527.01 g/mol.

Where can I buy (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide?

You can request a quote for (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (E)-N'-((5-bromothiophen-2-yl)methylene)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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