(E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide structure

(E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide

TL;DR: (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide (CAS 612811-68-4) is a chemical compound with molecular formula C24H18BrFN4O2S and molecular weight 524.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(E)-(5-bromo-2-fluorophenyl)methylideneamino]-2-[3-(2-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylacetamide

Also Known As: (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide, N'-[(E)-(5-bromo-2-fluorophenyl)methylidene]-2-{[3-(2-methylphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]sulfanyl}acetohydrazide, N-[(1E)-2-(5-bromo-2-fluorophenyl)-1-azavinyl]-2-[3-(2-methylphenyl)-4-oxo(3-h ydroquinazolin-2-ylthio)]acetamide, N-[(E)-(5-bromo-2-fluorophenyl)methylideneamino]-2-[3-(2-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylacetamide

CAS: 612811-68-4
Molecular Formula C24H18BrFN4O2S
Molecular Weight 524.03 g/mol
LogP 4.83812
Topological Polar Surface Area 76.35 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 524.0318
Heavy Atoms 33
Complexity 1437.9131

Chemical Identifiers

CAS Number 612811-68-4
SMILES CC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2SCC(=O)N/N=C/C4=C(C=CC(=C4)Br)F

Product Overview

(E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide (CAS 612811-68-4), with molecular formula C24H18BrFN4O2S and molecular weight 524.03 g/mol. IUPAC: N-[(E)-(5-bromo-2-fluorophenyl)methylideneamino]-2-[3-(2-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylacetamide.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide

XLogP
4.83812
TPSA (Topological Polar Surface Area)
76.35
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
33
Complexity
1437.9131
Exact Mass
524.0318
Monoisotopic Mass
524.0318
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide

The XLogP value of 4.83812 indicates that (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.35 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide. Following Lipinski's Rule of Five, (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

The CAS number of (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide is 612811-68-4.

What is the molecular formula of (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

The molecular formula of (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide is C24H18BrFN4O2S.

What is the molecular weight of (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

The molecular weight of (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide is 524.03 g/mol.

Where can I buy (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

You can request a quote for (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (E)-N'-(5-bromo-2-fluorobenzylidene)-2-((4-oxo-3-(o-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?