![4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline structure](/static/products/612/612500-85-3.png)
4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
TL;DR: 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline (CAS 612500-85-3) is a chemical compound with molecular formula C21H22ClFN4O4S and molecular weight 480.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(1-methylsulfonylpiperidin-4-yl)oxyquinazolin-4-amine
Also Known As: 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline, N-(3-chloro-2-fluoro-phenyl)-7-methoxy-6-[(1-methylsulfonyl-4-piperidyl)oxy]quinazolin-4-amine, N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(1-(methylsulfonyl)piperidin-4-yloxy)quinazolin-4-amine
| Molecular Formula | C21H22ClFN4O4S |
|---|---|
| Molecular Weight | 480.10 g/mol |
| LogP | 3.9773 |
| Topological Polar Surface Area | 93.65 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 480.10342 |
| Heavy Atoms | 32 |
| Complexity | 1250.0234 |
Chemical Identifiers
| CAS Number | 612500-85-3 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=CC=C3)Cl)F)OC4CCN(CC4)S(=O)(=O)C |
Product Overview
4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline (CAS 612500-85-3), with molecular formula C21H22ClFN4O4S and molecular weight 480.10 g/mol. IUPAC: N-(3-chloro-2-fluorophenyl)-7-methoxy-6-(1-methylsulfonylpiperidin-4-yl)oxyquinazolin-4-amine.
Chemical Property Profile of 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
Property Insights of 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline
The XLogP value of 3.9773 indicates that 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 93.65 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline. Following Lipinski's Rule of Five, 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline?
The CAS number of 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline is 612500-85-3.
What is the molecular formula of 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline?
The molecular formula of 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline is C21H22ClFN4O4S.
What is the molecular weight of 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline?
The molecular weight of 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline is 480.10 g/mol.
Where can I buy 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline?
You can request a quote for 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-(3-chloro-2-fluoroanilino)-6-{[1-(methylsulfonyl)piperidin-4-yl]oxy}-7-methoxyquinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.