考布他汀A4
TL;DR: 考布他汀A4 (CAS 61241-06-3) is a chemical compound with molecular formula C18H20O5 and molecular weight 316.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
考布他汀A4
2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol
Also Known As: Combretastatin A4, Combretastatin A-4, Combrestatin A4, Combretastatin 4, Combretastatin-A4
| Molecular Formula | C18H20O5 |
|---|---|
| Molecular Weight | 316.13 g/mol |
| LogP | 3.597 |
| Topological Polar Surface Area | 57.15 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 316.13107 |
| Heavy Atoms | 23 |
| Complexity | 681.5484 |
Chemical Identifiers
| CAS Number | 61241-06-3 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)O |
Product Overview
考布他汀A4 (CAS 61241-06-3), with molecular formula C18H20O5 and molecular weight 316.13 g/mol. IUPAC: 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol.
Chemical Property Profile of 考布他汀A4
Property Insights of 考布他汀A4
The XLogP value of 3.597 indicates that 考布他汀A4 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.15 Ų, 考布他汀A4 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 考布他汀A4 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 考布他汀A4?
The CAS number of 考布他汀A4 is 61241-06-3.
What is the molecular formula of 考布他汀A4?
The molecular formula of 考布他汀A4 is C18H20O5.
What is the molecular weight of 考布他汀A4?
The molecular weight of 考布他汀A4 is 316.13 g/mol.
Where can I buy 考布他汀A4?
You can request a quote for 考布他汀A4 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 考布他汀A4?
Yes, KEHONG BIO provides custom synthesis services for 考布他汀A4 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.