1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-
TL;DR: 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl- (CAS 61197-53-3) is a chemical compound with molecular formula C24H24ClN5O2 and molecular weight 449.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2E)-8-chloro-2-[[4-(2-hydroxyethyl)piperazin-1-yl]methylidene]-6-phenyl-4H-imidazo[1,2-a][1,4]benzodiazepin-1-one
Also Known As: 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-, (2E)-8-chloro-2-[[4-(2-hydroxyethyl)piperazin-1-yl]methylidene]-6-phenyl-4H-imidazo[1,2-a][1,4]benzodiazepin-1-one, RefChem:1057883
| Molecular Formula | C24H24ClN5O2 |
|---|---|
| Molecular Weight | 449.16 g/mol |
| LogP | 2.3874 |
| Topological Polar Surface Area | 71.74 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 449.16187 |
| Heavy Atoms | 32 |
| Complexity | 1120.4645 |
Chemical Identifiers
| CAS Number | 61197-53-3 |
|---|---|
| SMILES | C1CN(CCN1CCO)/C=C/2\C(=O)N3C(=N2)CN=C(C4=C3C=CC(=C4)Cl)C5=CC=CC=C5 |
Product Overview
1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl- (CAS 61197-53-3), with molecular formula C24H24ClN5O2 and molecular weight 449.16 g/mol. IUPAC: (2E)-8-chloro-2-[[4-(2-hydroxyethyl)piperazin-1-yl]methylidene]-6-phenyl-4H-imidazo[1,2-a][1,4]benzodiazepin-1-one.
Chemical Property Profile of 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-
Property Insights of 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-
The XLogP value of 2.3874 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-. The TPSA of 71.74 Ų falls within the moderate polarity range, balancing permeability and solubility for 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-. Following Lipinski's Rule of Five, 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl- has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-?
The CAS number of 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl- is 61197-53-3.
What is the molecular formula of 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-?
The molecular formula of 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl- is C24H24ClN5O2.
What is the molecular weight of 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-?
The molecular weight of 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl- is 449.16 g/mol.
Where can I buy 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-?
You can request a quote for 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl-?
Yes, KEHONG BIO provides custom synthesis services for 1H-Imidazo(1,2-a)(1,4)benzodiazepin-1-one, 2,4-dihydro-8-chloro-2-((4-(2-hydroxyethyl)-1-piperazinyl)methylene)-6-phenyl- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.