(E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one
TL;DR: (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one (CAS 609335-87-7) is a chemical compound with molecular formula C16H14N2O2 and molecular weight 266.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-3-methyl-4-[[5-(4-methylphenyl)furan-2-yl]methylidene]-1H-pyrazol-5-one
Also Known As: (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one, (4E)-3-methyl-4-[[5-(4-methylphenyl)furan-2-yl]methylidene]-1H-pyrazol-5-one, (4E)-5-methyl-4-{[5-(4-methylphenyl)furan-2-yl]methylidene}-4H-pyrazol-3-ol
| Molecular Formula | C16H14N2O2 |
|---|---|
| Molecular Weight | 266.11 g/mol |
| LogP | 3.14412 |
| Topological Polar Surface Area | 54.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 266.10553 |
| Heavy Atoms | 20 |
| Complexity | 721.19006 |
Chemical Identifiers
| CAS Number | 609335-87-7 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=CC=C(O2)/C=C/3\C(=NNC3=O)C |
Product Overview
(E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one (CAS 609335-87-7), with molecular formula C16H14N2O2 and molecular weight 266.11 g/mol. IUPAC: (4E)-3-methyl-4-[[5-(4-methylphenyl)furan-2-yl]methylidene]-1H-pyrazol-5-one.
Chemical Property Profile of (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one
Property Insights of (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one
The XLogP value of 3.14412 indicates that (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.6 Ų, (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one?
The CAS number of (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one is 609335-87-7.
What is the molecular formula of (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one?
The molecular formula of (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one is C16H14N2O2.
What is the molecular weight of (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one?
The molecular weight of (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one is 266.11 g/mol.
Where can I buy (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one?
You can request a quote for (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-methyl-4-((5-(p-tolyl)furan-2-yl)methylene)-1H-pyrazol-5(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.