Physostigmine methiodide structure

Physostigmine methiodide

TL;DR: Physostigmine methiodide (CAS 6091-11-8) is a chemical compound with molecular formula C16H24IN3O2 and molecular weight 417.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(3aR,8bS)-3,4,4,8b-tetramethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-4-ium-7-yl] N-methylcarbamate iodide

Also Known As: Physostigmine methiodide, Physostigmine, methiodide, [(3aR,8bS)-3,4,4,8b-tetramethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-4-ium-7-yl] N-methylcarbamate;iodide, Pyrrolo(2,3-b)indolium, 1,2,3,3a,8,8a-hexahydro-1,1,3a,8(or 1,3a,8,8)-tetramethyl-5-(((methylamino)carbonyl)oxy)-, iodide, (3aS-cis)-, [(3aR,8bS)-3,4,4,8b-tetramethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-4-ium-7-yl] N-methylcarbamate iodide

CAS: 6091-11-8
Molecular Formula C16H24IN3O2
Molecular Weight 417.09 g/mol
LogP -1.09
Topological Polar Surface Area 41.6 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 417.0913
Heavy Atoms 22
Complexity 439.0

Chemical Identifiers

CAS Number 6091-11-8
SMILES C[C@@]12CCN([C@@H]1[N+](C3=C2C=C(C=C3)OC(=O)NC)(C)C)C.[I-]
InChIKey SLSBBKOEHGUBBZ-XMZRARIVSA-N

Product Overview

Physostigmine methiodide (CAS 6091-11-8), with molecular formula C16H24IN3O2 and molecular weight 417.09 g/mol. IUPAC: [(3aR,8bS)-3,4,4,8b-tetramethyl-2,3a-dihydro-1H-pyrrolo[2,3-b]indol-4-ium-7-yl] N-methylcarbamate iodide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Physostigmine methiodide

XLogP
-1.09
TPSA (Topological Polar Surface Area)
41.6
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
22
Complexity
439.0
Exact Mass
417.0913
Monoisotopic Mass
417.0913
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Physostigmine methiodide

The XLogP value of -1.09 indicates that Physostigmine methiodide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 41.6 Ų, Physostigmine methiodide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Physostigmine methiodide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Physostigmine methiodide?

The CAS number of Physostigmine methiodide is 6091-11-8.

What is the molecular formula of Physostigmine methiodide?

The molecular formula of Physostigmine methiodide is C16H24IN3O2.

What is the molecular weight of Physostigmine methiodide?

The molecular weight of Physostigmine methiodide is 417.09 g/mol.

Where can I buy Physostigmine methiodide?

You can request a quote for Physostigmine methiodide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Physostigmine methiodide?

Yes, KEHONG BIO provides custom synthesis services for Physostigmine methiodide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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