![(E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one structure](/static/products/608/60878-55-9.png)
(E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
TL;DR: (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one (CAS 60878-55-9) is a chemical compound with molecular formula C25H31N3O and molecular weight 389.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10a-[(E)-2-[4-(diethylamino)phenyl]ethenyl]-10,10-dimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one
Also Known As: (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one, 10a-[(E)-2-[4-(diethylamino)phenyl]ethenyl]-10,10-dimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one, 10a-{(1E)-2-[4-(diethylamino)phenyl]vinyl}-10,10-dimethyl-1H,3H,4H-1,3-diazape rhydroino[1,2-a]indolin-2-one, 10a-{(E)-2-[4-(diethylamino)phenyl]ethenyl}-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
| Molecular Formula | C25H31N3O |
|---|---|
| Molecular Weight | 389.25 g/mol |
| LogP | 4.56 |
| Topological Polar Surface Area | 35.58 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 389.2467 |
| Heavy Atoms | 29 |
| Complexity | 927.3396 |
Chemical Identifiers
| CAS Number | 60878-55-9 |
|---|---|
| SMILES | CCN(CC)C1=CC=C(C=C1)/C=C/C23C(C4=CC=CC=C4N2CCC(=O)N3)(C)C |
Product Overview
(E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one (CAS 60878-55-9), with molecular formula C25H31N3O and molecular weight 389.25 g/mol. IUPAC: 10a-[(E)-2-[4-(diethylamino)phenyl]ethenyl]-10,10-dimethyl-3,4-dihydro-1H-pyrimido[1,2-a]indol-2-one.
Chemical Property Profile of (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
Property Insights of (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
The XLogP value of 4.56 indicates that (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.58 Ų, (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one?
The CAS number of (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one is 60878-55-9.
What is the molecular formula of (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one?
The molecular formula of (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one is C25H31N3O.
What is the molecular weight of (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one?
The molecular weight of (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one is 389.25 g/mol.
Where can I buy (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one?
You can request a quote for (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-10a-(4-(diethylamino)styryl)-10,10-dimethyl-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.