AF-399/41704154
TL;DR: AF-399/41704154 (CAS 608494-38-8) is a chemical compound with molecular formula C18H19FN2O3S and molecular weight 362.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
propan-2-yl 6-(4-fluorophenyl)-8-methyl-4-oxo-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate
Also Known As: AF-399/41704154, isopropyl 6-(4-fluorophenyl)-8-methyl-4-oxo-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate, propan-2-yl 6-(4-fluorophenyl)-8-methyl-4-oxo-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate, propan-2-yl 6-(4-fluorophenyl)-8-methyl-4-oxo-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate, isopropyl 6-(4-fluorophenyl)-8-methyl-4-oxo-2,3,4,6-tetrahydropyrimido[2,1-b][1,3]thiazine-7-carboxylate
| Molecular Formula | C18H19FN2O3S |
|---|---|
| Molecular Weight | 362.11 g/mol |
| LogP | 3.4275 |
| Topological Polar Surface Area | 58.97 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 362.11005 |
| Heavy Atoms | 25 |
| Complexity | 771.03076 |
Chemical Identifiers
| CAS Number | 608494-38-8 |
|---|---|
| SMILES | CC1=C(C(N2C(=O)CCSC2=N1)C3=CC=C(C=C3)F)C(=O)OC(C)C |
Product Overview
AF-399/41704154 (CAS 608494-38-8), with molecular formula C18H19FN2O3S and molecular weight 362.11 g/mol. IUPAC: propan-2-yl 6-(4-fluorophenyl)-8-methyl-4-oxo-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate.
Chemical Property Profile of AF-399/41704154
Property Insights of AF-399/41704154
The XLogP value of 3.4275 indicates that AF-399/41704154 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.97 Ų, AF-399/41704154 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/41704154 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/41704154?
The CAS number of AF-399/41704154 is 608494-38-8.
What is the molecular formula of AF-399/41704154?
The molecular formula of AF-399/41704154 is C18H19FN2O3S.
What is the molecular weight of AF-399/41704154?
The molecular weight of AF-399/41704154 is 362.11 g/mol.
Where can I buy AF-399/41704154?
You can request a quote for AF-399/41704154 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/41704154?
Yes, KEHONG BIO provides custom synthesis services for AF-399/41704154 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.