(E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide
TL;DR: (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide (CAS 608491-29-8) is a chemical compound with molecular formula C23H21N3O2S and molecular weight 403.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-[(E)-1-cyano-2-(2-ethoxyphenyl)ethenyl]-4-(4-methylphenyl)-1,3-thiazol-5-yl]acetamide
Also Known As: (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide, N-[2-[(E)-1-cyano-2-(2-ethoxyphenyl)ethenyl]-4-(4-methylphenyl)-1,3-thiazol-5-yl]acetamide, N-{2-[(1E)-1-CYANO-2-(2-ETHOXYPHENYL)ETH-1-EN-1-YL]-4-(4-METHYLPHENYL)-1,3-THIAZOL-5-YL}ACETAMIDE, N-{2-[(E)-1-cyano-2-(2-ethoxyphenyl)ethenyl]-4-(4-methylphenyl)-1,3-thiazol-5-yl}acetamide
| Molecular Formula | C23H21N3O2S |
|---|---|
| Molecular Weight | 403.14 g/mol |
| LogP | 5.5398 |
| Topological Polar Surface Area | 75.01 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 403.13544 |
| Heavy Atoms | 29 |
| Complexity | 1092.0559 |
Chemical Identifiers
| CAS Number | 608491-29-8 |
|---|---|
| SMILES | CCOC1=CC=CC=C1/C=C(\C#N)/C2=NC(=C(S2)NC(=O)C)C3=CC=C(C=C3)C |
Product Overview
(E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide (CAS 608491-29-8), with molecular formula C23H21N3O2S and molecular weight 403.14 g/mol. IUPAC: N-[2-[(E)-1-cyano-2-(2-ethoxyphenyl)ethenyl]-4-(4-methylphenyl)-1,3-thiazol-5-yl]acetamide.
Chemical Property Profile of (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide
Property Insights of (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide
The XLogP value of 5.5398 indicates that (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.01 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide. Following Lipinski's Rule of Five, (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
The CAS number of (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide is 608491-29-8.
What is the molecular formula of (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
The molecular formula of (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide is C23H21N3O2S.
What is the molecular weight of (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
The molecular weight of (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide is 403.14 g/mol.
Where can I buy (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
You can request a quote for (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(2-(1-cyano-2-(2-ethoxyphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.