阿普密蘭特
TL;DR: 阿普密蘭特 (CAS 608141-41-9) is a chemical compound with molecular formula C22H24N2O7S and molecular weight 460.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
阿普密蘭特
N-[2-[(1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide
Also Known As: (R)-Apremilast, Apremilast R-Isomer, Apremilast Impurity 1, Apremilast Impurity 2, (R)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
| Molecular Formula | C22H24N2O7S |
|---|---|
| Molecular Weight | 460.13 g/mol |
| LogP | 2.4342 |
| Topological Polar Surface Area | 119.08 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 460.13043 |
| Heavy Atoms | 32 |
| Complexity | 1190.7606 |
Chemical Identifiers
| CAS Number | 608141-41-9 |
|---|---|
| SMILES | CCOC1=C(C=CC(=C1)[C@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC |
Product Overview
阿普密蘭特 (CAS 608141-41-9), with molecular formula C22H24N2O7S and molecular weight 460.13 g/mol. IUPAC: N-[2-[(1R)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide.
Chemical Property Profile of 阿普密蘭特
Property Insights of 阿普密蘭特
The XLogP value of 2.4342 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 阿普密蘭特. The TPSA of 119.08 Ų falls within the moderate polarity range, balancing permeability and solubility for 阿普密蘭特. Following Lipinski's Rule of Five, 阿普密蘭特 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 阿普密蘭特?
The CAS number of 阿普密蘭特 is 608141-41-9.
What is the molecular formula of 阿普密蘭特?
The molecular formula of 阿普密蘭特 is C22H24N2O7S.
What is the molecular weight of 阿普密蘭特?
The molecular weight of 阿普密蘭特 is 460.13 g/mol.
Where can I buy 阿普密蘭特?
You can request a quote for 阿普密蘭特 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 阿普密蘭特?
Yes, KEHONG BIO provides custom synthesis services for 阿普密蘭特 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.