2,4-Dibromo Estrone structure

2,4-Dibromo Estrone

TL;DR: 2,4-Dibromo Estrone (CAS 60788-62-7) is a chemical compound with molecular formula C18H20Br2O2 and molecular weight 425.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8R,9S,13S,14S)-2,4-dibromo-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one

Also Known As: 2,4-Dibromo Estrone, 2,4-Dibromoestrone, Nilestriol Impurity 3, 2,3,5(10)-trien-3-ol-17-one, NCI60_029597

CAS: 60788-62-7
Molecular Formula C18H20Br2O2
Molecular Weight 425.98 g/mol
LogP 4.5
Topological Polar Surface Area 37.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 0
Exact Mass 425.983
Heavy Atoms 22
Complexity 482.0

Chemical Identifiers

CAS Number 60788-62-7
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C(C(=C(C=C34)Br)O)Br
InChIKey HEWYVIICKQEYPO-HIONPOMWSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (3 patents) Pharmaceutical Intermediates (1 patents)

Product Overview

2,4-Dibromo Estrone (CAS 60788-62-7), with molecular formula C18H20Br2O2 and molecular weight 425.98 g/mol. IUPAC: (8R,9S,13S,14S)-2,4-dibromo-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2,4-Dibromo Estrone

XLogP
4.5
TPSA (Topological Polar Surface Area)
37.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
22
Complexity
482.0
Exact Mass
425.983
Monoisotopic Mass
425.983
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2,4-Dibromo Estrone

The XLogP value of 4.5 indicates that 2,4-Dibromo Estrone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 2,4-Dibromo Estrone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,4-Dibromo Estrone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2,4-Dibromo Estrone?

The CAS number of 2,4-Dibromo Estrone is 60788-62-7.

What is the molecular formula of 2,4-Dibromo Estrone?

The molecular formula of 2,4-Dibromo Estrone is C18H20Br2O2.

What is the molecular weight of 2,4-Dibromo Estrone?

The molecular weight of 2,4-Dibromo Estrone is 425.98 g/mol.

Where can I buy 2,4-Dibromo Estrone?

You can request a quote for 2,4-Dibromo Estrone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2,4-Dibromo Estrone?

Yes, KEHONG BIO provides custom synthesis services for 2,4-Dibromo Estrone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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