noscapine structure

noscapine

TL;DR: noscapine (CAS 60784-57-8) is a chemical compound with molecular formula C22H23NO7 and molecular weight 413.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one

Also Known As: noscapine, KST-1A6466, (3r)-6,7-dimethoxy-3-[(5s)-4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-2-benzofuran-1(3h)-one, 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one, 6,7-dimethoxy-3-[(5s)-4-methoxy-6-methyl-7,8-dihydro-5h-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3h-isobenzofuran-1-one

CAS: 60784-57-8
Molecular Formula C22H23NO7
Molecular Weight 413.15 g/mol
LogP 2.7
Topological Polar Surface Area 75.7 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 4
Exact Mass 413.14746
Heavy Atoms 30
Complexity 647.0

Chemical Identifiers

CAS Number 60784-57-8
SMILES CN1CCC2=CC3=C(C(=C2[C@H]1C4C5=C(C(=C(C=C5)OC)OC)C(=O)O4)OC)OCO3
InChIKey AKNNEGZIBPJZJG-ZENAZSQFSA-N

Product Overview

noscapine (CAS 60784-57-8), with molecular formula C22H23NO7 and molecular weight 413.15 g/mol. IUPAC: 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of noscapine

XLogP
2.7
TPSA (Topological Polar Surface Area)
75.7
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
4
Heavy Atoms
30
Complexity
647.0
Exact Mass
413.14746
Monoisotopic Mass
413.14746
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of noscapine

The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for noscapine. The TPSA of 75.7 Ų falls within the moderate polarity range, balancing permeability and solubility for noscapine. Following Lipinski's Rule of Five, noscapine has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of noscapine?

The CAS number of noscapine is 60784-57-8.

What is the molecular formula of noscapine?

The molecular formula of noscapine is C22H23NO7.

What is the molecular weight of noscapine?

The molecular weight of noscapine is 413.15 g/mol.

Where can I buy noscapine?

You can request a quote for noscapine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for noscapine?

Yes, KEHONG BIO provides custom synthesis services for noscapine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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