Lobeglitazone
TL;DR: Lobeglitazone (CAS 607723-33-1) is a chemical compound with molecular formula C24H24N4O5S and molecular weight 480.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[[4-[2-[[6-(4-methoxyphenoxy)pyrimidin-4-yl]-methylamino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Also Known As: Lobeglitazone, lobeglitazona, lobeglitazonum, Duvie, Lobeglitazone [INN]
| Molecular Formula | C24H24N4O5S |
|---|---|
| Molecular Weight | 480.15 g/mol |
| LogP | 3.6868 |
| Topological Polar Surface Area | 102.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 480.14673 |
| Heavy Atoms | 34 |
| Complexity | 1140.8601 |
Chemical Identifiers
| CAS Number | 607723-33-1 |
|---|---|
| SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC(=NC=N3)OC4=CC=C(C=C4)OC |
Product Overview
Lobeglitazone (CAS 607723-33-1), with molecular formula C24H24N4O5S and molecular weight 480.15 g/mol. IUPAC: 5-[[4-[2-[[6-(4-methoxyphenoxy)pyrimidin-4-yl]-methylamino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione.
Chemical Property Profile of Lobeglitazone
Property Insights of Lobeglitazone
The XLogP value of 3.6868 indicates that Lobeglitazone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 102.88 Ų falls within the moderate polarity range, balancing permeability and solubility for Lobeglitazone. Following Lipinski's Rule of Five, Lobeglitazone has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lobeglitazone?
The CAS number of Lobeglitazone is 607723-33-1.
What is the molecular formula of Lobeglitazone?
The molecular formula of Lobeglitazone is C24H24N4O5S.
What is the molecular weight of Lobeglitazone?
The molecular weight of Lobeglitazone is 480.15 g/mol.
Where can I buy Lobeglitazone?
You can request a quote for Lobeglitazone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lobeglitazone?
Yes, KEHONG BIO provides custom synthesis services for Lobeglitazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.