AF-399/41622412
TL;DR: AF-399/41622412 (CAS 606959-08-4) is a chemical compound with molecular formula C16H8Cl2N4OS and molecular weight 373.98 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(2,4-dichlorophenyl)methylidene]-2-pyridin-4-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
Also Known As: AF-399/41622412, (5Z)-5-[(2,4-dichlorophenyl)methylidene]-2-pyridin-4-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one, 5-(2,4-dichlorobenzylidene)-2-(4-pyridinyl)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
| Molecular Formula | C16H8Cl2N4OS |
|---|---|
| Molecular Weight | 373.98 g/mol |
| LogP | 3.0675 |
| Topological Polar Surface Area | 60.15 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 373.97958 |
| Heavy Atoms | 24 |
| Complexity | 1154.2509 |
Chemical Identifiers
| CAS Number | 606959-08-4 |
|---|---|
| SMILES | C1=CC(=C(C=C1Cl)Cl)/C=C\2/C(=O)N3C(=NC(=N3)C4=CC=NC=C4)S2 |
Product Overview
AF-399/41622412 (CAS 606959-08-4), with molecular formula C16H8Cl2N4OS and molecular weight 373.98 g/mol. IUPAC: (5Z)-5-[(2,4-dichlorophenyl)methylidene]-2-pyridin-4-yl-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one.
Chemical Property Profile of AF-399/41622412
Property Insights of AF-399/41622412
The XLogP value of 3.0675 indicates that AF-399/41622412 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.15 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/41622412. Following Lipinski's Rule of Five, AF-399/41622412 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/41622412?
The CAS number of AF-399/41622412 is 606959-08-4.
What is the molecular formula of AF-399/41622412?
The molecular formula of AF-399/41622412 is C16H8Cl2N4OS.
What is the molecular weight of AF-399/41622412?
The molecular weight of AF-399/41622412 is 373.98 g/mol.
Where can I buy AF-399/41622412?
You can request a quote for AF-399/41622412 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/41622412?
Yes, KEHONG BIO provides custom synthesis services for AF-399/41622412 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.