N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide
TL;DR: N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide (CAS 606132-13-2) is a chemical compound with molecular formula C12H7F4N3O and molecular weight 285.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-fluoro-5-(trifluoromethyl)phenyl]pyrazine-2-carboxamide
Also Known As: ASN 06977415, N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide, N-[2-Fluoro-5-(trifluoromethyl)phenyl]-2-pyrazinecarboxamide, N-[2-fluoro-5-(trifluoromethyl)phenyl]pyrazine-2-carboxamide, Pyrazinecarboxamide, N-[2-fluoro-5-(trifluoromethyl)phenyl]- (9CI)
| Molecular Formula | C12H7F4N3O |
|---|---|
| Molecular Weight | 285.05 g/mol |
| LogP | 2.8868 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 285.05252 |
| Heavy Atoms | 20 |
| Complexity | 628.3447 |
Chemical Identifiers
| CAS Number | 606132-13-2 |
|---|---|
| SMILES | C1=CC(=C(C=C1C(F)(F)F)NC(=O)C2=NC=CN=C2)F |
Product Overview
N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide (CAS 606132-13-2), with molecular formula C12H7F4N3O and molecular weight 285.05 g/mol. IUPAC: N-[2-fluoro-5-(trifluoromethyl)phenyl]pyrazine-2-carboxamide.
Chemical Property Profile of N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide
Property Insights of N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide
The XLogP value of 2.8868 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide. With a topological polar surface area (TPSA) of 54.88 Ų, N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide?
The CAS number of N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide is 606132-13-2.
What is the molecular formula of N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide?
The molecular formula of N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide is C12H7F4N3O.
What is the molecular weight of N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide?
The molecular weight of N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide is 285.05 g/mol.
Where can I buy N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide?
You can request a quote for N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2-Fluoro-5-(trifluoromethyl)phenyl)pyrazine-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.