3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide
TL;DR: 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide (CAS 606090-34-0) is a chemical compound with molecular formula C19H18ClFN4S and molecular weight 388.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide
Also Known As: 1-PIPERIDINECARBOTHIOAMIDE, 3-(5-CHLORO-1H-BENZIMIDAZOL-2-YL)-N-(4-FLUOROPHENYL)-, 1-Piperidinecarbothioamide, 3-(5-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)- (9CI), 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide, 3-(6-chloro-1H-benzoimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide
| Molecular Formula | C19H18ClFN4S |
|---|---|
| Molecular Weight | 388.09 g/mol |
| LogP | 4.9318 |
| Topological Polar Surface Area | 43.95 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 388.09247 |
| Heavy Atoms | 26 |
| Complexity | 940.36707 |
Chemical Identifiers
| CAS Number | 606090-34-0 |
|---|---|
| SMILES | C1CC(CN(C1)C(=S)NC2=CC=C(C=C2)F)C3=NC4=C(N3)C=C(C=C4)Cl |
Product Overview
3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide (CAS 606090-34-0), with molecular formula C19H18ClFN4S and molecular weight 388.09 g/mol. IUPAC: 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide.
Chemical Property Profile of 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide
Property Insights of 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide
The XLogP value of 4.9318 indicates that 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.95 Ų, 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide?
The CAS number of 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide is 606090-34-0.
What is the molecular formula of 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide?
The molecular formula of 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide is C19H18ClFN4S.
What is the molecular weight of 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide?
The molecular weight of 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide is 388.09 g/mol.
Where can I buy 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide?
You can request a quote for 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide?
Yes, KEHONG BIO provides custom synthesis services for 3-(6-chloro-1H-benzimidazol-2-yl)-N-(4-fluorophenyl)piperidine-1-carbothioamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.