4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide
TL;DR: 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide (CAS 606087-84-7) is a chemical compound with molecular formula C18H24N4S2 and molecular weight 360.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-N-propylpiperazine-1-carbothioamide
Also Known As: ASN 06588829, 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide, 1-PIPERAZINECARBOTHIOAMIDE, 4-[4-(4-METHYLPHENYL)-2-THIAZOLYL]-N-PROPYL-, 1-Piperazinecarbothioamide, 4-[4-(4-methylphenyl)-2-thiazolyl]-N-propyl- (9CI), 4-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-N-propylpiperazine-1-carbothioamide
| Molecular Formula | C18H24N4S2 |
|---|---|
| Molecular Weight | 360.14 g/mol |
| LogP | 3.52502 |
| Topological Polar Surface Area | 31.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 360.14423 |
| Heavy Atoms | 24 |
| Complexity | 672.58215 |
Chemical Identifiers
| CAS Number | 606087-84-7 |
|---|---|
| SMILES | CCCNC(=S)N1CCN(CC1)C2=NC(=CS2)C3=CC=C(C=C3)C |
Product Overview
4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide (CAS 606087-84-7), with molecular formula C18H24N4S2 and molecular weight 360.14 g/mol. IUPAC: 4-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-N-propylpiperazine-1-carbothioamide.
Chemical Property Profile of 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide
Property Insights of 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide
The XLogP value of 3.52502 indicates that 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 31.4 Ų, 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide?
The CAS number of 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide is 606087-84-7.
What is the molecular formula of 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide?
The molecular formula of 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide is C18H24N4S2.
What is the molecular weight of 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide?
The molecular weight of 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide is 360.14 g/mol.
Where can I buy 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide?
You can request a quote for 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-p-Tolyl-thiazol-2-yl)-piperazine-1-carbothioic acid propylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.