2-Chloro-2',5'-difluoroacetophenone
TL;DR: 2-Chloro-2',5'-difluoroacetophenone (CAS 60469-67-2) is a chemical compound with molecular formula C8H5ClF2O and molecular weight 190.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-1-(2,5-difluorophenyl)ethanone
Also Known As: 2-chloro-2',5'-difluoroacetophenone, 2-chloro-1-(2,5-difluorophenyl)ethanone, 2-Chloro-2,5-Difluoroacetophenone, 2,5-difluorophenacyl chloride, 2-chloro-1-(2,5-difluorophenyl)ethan-1-one
| Molecular Formula | C8H5ClF2O |
|---|---|
| Molecular Weight | 190.00 g/mol |
| LogP | 2.3863 |
| Topological Polar Surface Area | 17.07 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 189.9997 |
| Heavy Atoms | 12 |
| Complexity | 311.9262 |
Chemical Identifiers
| CAS Number | 60469-67-2 |
|---|---|
| SMILES | C1=CC(=C(C=C1F)C(=O)CCl)F |
Product Overview
2-Chloro-2',5'-difluoroacetophenone (CAS 60469-67-2), with molecular formula C8H5ClF2O and molecular weight 190.00 g/mol. IUPAC: 2-chloro-1-(2,5-difluorophenyl)ethanone.
Chemical Property Profile of 2-Chloro-2',5'-difluoroacetophenone
Property Insights of 2-Chloro-2',5'-difluoroacetophenone
The XLogP value of 2.3863 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Chloro-2',5'-difluoroacetophenone. With a topological polar surface area (TPSA) of 17.07 Ų, 2-Chloro-2',5'-difluoroacetophenone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chloro-2',5'-difluoroacetophenone has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Chloro-2',5'-difluoroacetophenone?
The CAS number of 2-Chloro-2',5'-difluoroacetophenone is 60469-67-2.
What is the molecular formula of 2-Chloro-2',5'-difluoroacetophenone?
The molecular formula of 2-Chloro-2',5'-difluoroacetophenone is C8H5ClF2O.
What is the molecular weight of 2-Chloro-2',5'-difluoroacetophenone?
The molecular weight of 2-Chloro-2',5'-difluoroacetophenone is 190.00 g/mol.
Where can I buy 2-Chloro-2',5'-difluoroacetophenone?
You can request a quote for 2-Chloro-2',5'-difluoroacetophenone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Chloro-2',5'-difluoroacetophenone?
Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-2',5'-difluoroacetophenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.