Bufenadrine structure

Bufenadrine

TL;DR: Bufenadrine (CAS 604-74-0) is a chemical compound with molecular formula C21H29NO and molecular weight 311.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[(2-tert-butylphenyl)-phenylmethoxy]-N,N-dimethylethanamine

Also Known As: Bufenadrine, Bufenadrina, Buphenadrin, Bufenadrinum, Bufenadrine [INN]

CAS: 604-74-0
Molecular Formula C21H29NO
Molecular Weight 311.22 g/mol
LogP 5.1
Topological Polar Surface Area 12.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 7
Exact Mass 311.2249
Heavy Atoms 23
Complexity 327.0

Chemical Identifiers

CAS Number 604-74-0
SMILES CC(C)(C)C1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C
InChIKey OGNRRAFRDFGFKA-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Organic Building Blocks (1 patents) Pharmaceutical Intermediates (14 patents)

Product Overview

Bufenadrine (CAS 604-74-0), with molecular formula C21H29NO and molecular weight 311.22 g/mol. IUPAC: 2-[(2-tert-butylphenyl)-phenylmethoxy]-N,N-dimethylethanamine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Bufenadrine

XLogP
5.1
TPSA (Topological Polar Surface Area)
12.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
7
Heavy Atoms
23
Complexity
327.0
Exact Mass
311.2249
Monoisotopic Mass
311.2249
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Bufenadrine

The XLogP value of 5.1 indicates that Bufenadrine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.5 Ų, Bufenadrine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bufenadrine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Bufenadrine?

The CAS number of Bufenadrine is 604-74-0.

What is the molecular formula of Bufenadrine?

The molecular formula of Bufenadrine is C21H29NO.

What is the molecular weight of Bufenadrine?

The molecular weight of Bufenadrine is 311.22 g/mol.

Where can I buy Bufenadrine?

You can request a quote for Bufenadrine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Bufenadrine?

Yes, KEHONG BIO provides custom synthesis services for Bufenadrine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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