Nifedipine-hydrochloride
TL;DR: Nifedipine-hydrochloride (CAS 60299-11-8) is a chemical compound with molecular formula C17H19ClN2O6 and molecular weight 382.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride
Also Known As: Nifedipine hydrochloride, Coracten XL, Nifedipine HCl, Nifedipine-hydrochloride, Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate monohydrochloride
| Molecular Formula | C17H19ClN2O6 |
|---|---|
| Molecular Weight | 382.09 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 110.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 382.09317 |
| Heavy Atoms | 26 |
| Complexity | 608.0 |
Chemical Identifiers
| CAS Number | 60299-11-8 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC.Cl |
| InChIKey | ISQGFMPRCDAJRT-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Nifedipine-hydrochloride (CAS 60299-11-8), with molecular formula C17H19ClN2O6 and molecular weight 382.09 g/mol. IUPAC: dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride.
Chemical Property Profile of Nifedipine-hydrochloride
Property Insights of Nifedipine-hydrochloride
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nifedipine-hydrochloride. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nifedipine-hydrochloride. Following Lipinski's Rule of Five, Nifedipine-hydrochloride has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nifedipine-hydrochloride?
The CAS number of Nifedipine-hydrochloride is 60299-11-8.
What is the molecular formula of Nifedipine-hydrochloride?
The molecular formula of Nifedipine-hydrochloride is C17H19ClN2O6.
What is the molecular weight of Nifedipine-hydrochloride?
The molecular weight of Nifedipine-hydrochloride is 382.09 g/mol.
Where can I buy Nifedipine-hydrochloride?
You can request a quote for Nifedipine-hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nifedipine-hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Nifedipine-hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.