Clopipazan structure

Clopipazan

TL;DR: Clopipazan (CAS 60085-78-1) is a chemical compound with molecular formula C19H18ClNO and molecular weight 311.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-(2-chloroxanthen-9-ylidene)-1-methylpiperidine

Also Known As: Clopipazan [INN], clopipazanum, Clopipazan (free base), 4-(2-Chloroxanthen-9-ylidene)-1-methylpiperidine, PDSP1_000020

CAS: 60085-78-1
Molecular Formula C19H18ClNO
Molecular Weight 311.11 g/mol
LogP 4.0
Topological Polar Surface Area 12.5 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 0
Exact Mass 311.1077
Heavy Atoms 22
Complexity 439.0

Chemical Identifiers

CAS Number 60085-78-1
SMILES CN1CCC(=C2C3=CC=CC=C3OC4=C2C=C(C=C4)Cl)CC1
InChIKey QUXRAOQDUJFWIA-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (42 patents)

Product Overview

Clopipazan (CAS 60085-78-1), with molecular formula C19H18ClNO and molecular weight 311.11 g/mol. IUPAC: 4-(2-chloroxanthen-9-ylidene)-1-methylpiperidine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Clopipazan

XLogP
4.0
TPSA (Topological Polar Surface Area)
12.5
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
0
Heavy Atoms
22
Complexity
439.0
Exact Mass
311.1077
Monoisotopic Mass
311.1077
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Clopipazan

The XLogP value of 4.0 indicates that Clopipazan is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.5 Ų, Clopipazan exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Clopipazan has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Clopipazan?

The CAS number of Clopipazan is 60085-78-1.

What is the molecular formula of Clopipazan?

The molecular formula of Clopipazan is C19H18ClNO.

What is the molecular weight of Clopipazan?

The molecular weight of Clopipazan is 311.11 g/mol.

Where can I buy Clopipazan?

You can request a quote for Clopipazan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Clopipazan?

Yes, KEHONG BIO provides custom synthesis services for Clopipazan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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