Roxibolone structure

Roxibolone

TL;DR: Roxibolone (CAS 60023-92-9) is a chemical compound with molecular formula C21H28O5 and molecular weight 360.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,9S,10R,11S,13S,14S,17S)-11,17-dihydroxy-10,13,17-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2-carboxylic acid

Also Known As: Roxibolone, Roxibolonum, roxibolona, Roxibolono, Roxibolone [INN]

CAS: 60023-92-9
Molecular Formula C21H28O5
Molecular Weight 360.19 g/mol
LogP 2.8
Topological Polar Surface Area 94.8 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 5
Rotatable Bonds 1
Exact Mass 360.19366
Heavy Atoms 26
Complexity 752.0

Chemical Identifiers

CAS Number 60023-92-9
SMILES C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C(=C[C@]34C)C(=O)O)O)C)O
InChIKey JOFBZBDWOWPUMO-QARKFJNLSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (1 patents) Organic Building Blocks (1 patents) Pharmaceutical Intermediates (78 patents)

Product Overview

Roxibolone (CAS 60023-92-9), with molecular formula C21H28O5 and molecular weight 360.19 g/mol. IUPAC: (8S,9S,10R,11S,13S,14S,17S)-11,17-dihydroxy-10,13,17-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Roxibolone

XLogP
2.8
TPSA (Topological Polar Surface Area)
94.8
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
5
Rotatable Bonds
1
Heavy Atoms
26
Complexity
752.0
Exact Mass
360.19366
Monoisotopic Mass
360.19366
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Roxibolone

The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Roxibolone. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Roxibolone. Following Lipinski's Rule of Five, Roxibolone has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Roxibolone?

The CAS number of Roxibolone is 60023-92-9.

What is the molecular formula of Roxibolone?

The molecular formula of Roxibolone is C21H28O5.

What is the molecular weight of Roxibolone?

The molecular weight of Roxibolone is 360.19 g/mol.

Where can I buy Roxibolone?

You can request a quote for Roxibolone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Roxibolone?

Yes, KEHONG BIO provides custom synthesis services for Roxibolone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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