(-)-Quinine dihydrochloride
TL;DR: (-)-Quinine dihydrochloride (CAS 60-93-5) is a chemical compound with molecular formula C20H26Cl2N2O2 and molecular weight 396.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;dihydrochloride
Also Known As: Quinine dihydrochloride, Quinine bimuriate, Quinine 2HCl, Quinine HCl, Acid quinine hydrochloride
| Molecular Formula | C20H26Cl2N2O2 |
|---|---|
| Molecular Weight | 396.14 g/mol |
| LogP | 4.02 |
| Topological Polar Surface Area | 45.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 396.13715 |
| Heavy Atoms | 26 |
| Complexity | 457.0 |
Chemical Identifiers
| CAS Number | 60-93-5 |
|---|---|
| SMILES | COC1=CC2=C(C=CN=C2C=C1)[C@H]([C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)O.Cl.Cl |
| InChIKey | NNKXWRRDHYTHFP-HZQSTTLBSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
(-)-Quinine dihydrochloride (CAS 60-93-5), with molecular formula C20H26Cl2N2O2 and molecular weight 396.14 g/mol. IUPAC: (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;dihydrochloride.
Chemical Property Profile of (-)-Quinine dihydrochloride
Property Insights of (-)-Quinine dihydrochloride
The XLogP value of 4.02 indicates that (-)-Quinine dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.6 Ų, (-)-Quinine dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (-)-Quinine dihydrochloride has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (-)-Quinine dihydrochloride?
The CAS number of (-)-Quinine dihydrochloride is 60-93-5.
What is the molecular formula of (-)-Quinine dihydrochloride?
The molecular formula of (-)-Quinine dihydrochloride is C20H26Cl2N2O2.
What is the molecular weight of (-)-Quinine dihydrochloride?
The molecular weight of (-)-Quinine dihydrochloride is 396.14 g/mol.
Where can I buy (-)-Quinine dihydrochloride?
You can request a quote for (-)-Quinine dihydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (-)-Quinine dihydrochloride?
Yes, KEHONG BIO provides custom synthesis services for (-)-Quinine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.