6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one
TL;DR: 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one (CAS 599151-23-2) is a chemical compound with molecular formula C18H16F3NO3 and molecular weight 351.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6,7-dimethoxy-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-quinolin-2-one
Also Known As: BAS 09588608, A2912/0122749, 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one, 6,7-dimethoxy-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-quinolin-2-one, 6,7-dimethoxy-4-[4-(trifluoromethyl)phenyl]-1,3,4-trihydroquinolin-2-one
| Molecular Formula | C18H16F3NO3 |
|---|---|
| Molecular Weight | 351.11 g/mol |
| LogP | 4.1967 |
| Topological Polar Surface Area | 47.56 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 351.10822 |
| Heavy Atoms | 25 |
| Complexity | 800.449 |
Chemical Identifiers
| CAS Number | 599151-23-2 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C(CC(=O)N2)C3=CC=C(C=C3)C(F)(F)F)OC |
Product Overview
6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one (CAS 599151-23-2), with molecular formula C18H16F3NO3 and molecular weight 351.11 g/mol. IUPAC: 6,7-dimethoxy-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-quinolin-2-one.
Chemical Property Profile of 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one
Property Insights of 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one
The XLogP value of 4.1967 indicates that 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.56 Ų, 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one?
The CAS number of 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one is 599151-23-2.
What is the molecular formula of 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one?
The molecular formula of 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one is C18H16F3NO3.
What is the molecular weight of 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one?
The molecular weight of 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one is 351.11 g/mol.
Where can I buy 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one?
You can request a quote for 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 6,7-Dimethoxy-4-(4-trifluoromethyl-phenyl)-3,4-dihydro-1H-quinolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.