Npm-II
TL;DR: Npm-II (CAS 59875-58-0) is a chemical compound with molecular formula C26H27N3O6 and molecular weight 477.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-O-[2-[benzyl(methyl)amino]ethyl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
Also Known As: Npm-II, Dehydro Nicardipine, Nicardipine pyridine metabolite II, Dehydro Nicardipine Hydrochloride, Nicardipine EP Impurity A
| Molecular Formula | C26H27N3O6 |
|---|---|
| Molecular Weight | 477.19 g/mol |
| LogP | 4.34904 |
| Topological Polar Surface Area | 111.87 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 9 |
| Exact Mass | 477.18997 |
| Heavy Atoms | 35 |
| Complexity | 1243.3346 |
Chemical Identifiers
| CAS Number | 59875-58-0 |
|---|---|
| SMILES | CC1=C(C(=C(C(=N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC |
Product Overview
Npm-II (CAS 59875-58-0), with molecular formula C26H27N3O6 and molecular weight 477.19 g/mol. IUPAC: 3-O-[2-[benzyl(methyl)amino]ethyl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate.
Chemical Property Profile of Npm-II
Property Insights of Npm-II
The XLogP value of 4.34904 indicates that Npm-II is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 111.87 Ų falls within the moderate polarity range, balancing permeability and solubility for Npm-II. Following Lipinski's Rule of Five, Npm-II has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Npm-II?
The CAS number of Npm-II is 59875-58-0.
What is the molecular formula of Npm-II?
The molecular formula of Npm-II is C26H27N3O6.
What is the molecular weight of Npm-II?
The molecular weight of Npm-II is 477.19 g/mol.
Where can I buy Npm-II?
You can request a quote for Npm-II directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Npm-II?
Yes, KEHONG BIO provides custom synthesis services for Npm-II and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.