DihydroCsA structure

DihydroCsA

TL;DR: DihydroCsA (CAS 59865-15-5) is a chemical compound with molecular formula C62H113N11O12 and molecular weight 1203.86 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

Also Known As: Dihydrocyclosporin A, DihydroCsA, Cyclosporin A der., Dihydro Cyclosporin A, Cyclosporin A, 6-((3R,4R)-3-hydroxy-N,4-dimethyl-L-2-aminooctanoic acid)-

CAS: 59865-15-5
Molecular Formula C62H113N11O12
Molecular Weight 1203.86 g/mol
LogP 8.2
Topological Polar Surface Area 279.0 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 12
Rotatable Bonds 16
Exact Mass 1203.857
Heavy Atoms 85
Complexity 2280.0

Chemical Identifiers

CAS Number 59865-15-5
SMILES CCCC[C@@H](C)[C@H](C1C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)CC)O
InChIKey TYFOVYYNQGNDKH-CJOIJTDBSA-N

Product Overview

DihydroCsA (CAS 59865-15-5), with molecular formula C62H113N11O12 and molecular weight 1203.86 g/mol. IUPAC: (3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of DihydroCsA

XLogP
8.2
TPSA (Topological Polar Surface Area)
279.0
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
12
Rotatable Bonds
16
Heavy Atoms
85
Complexity
2280.0
Exact Mass
1203.857
Monoisotopic Mass
1203.857
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of DihydroCsA

The XLogP value of 8.2 indicates that DihydroCsA is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 279.0 Ų indicates high polarity, suggesting DihydroCsA may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, DihydroCsA has 5 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of DihydroCsA?

The CAS number of DihydroCsA is 59865-15-5.

What is the molecular formula of DihydroCsA?

The molecular formula of DihydroCsA is C62H113N11O12.

What is the molecular weight of DihydroCsA?

The molecular weight of DihydroCsA is 1203.86 g/mol.

Where can I buy DihydroCsA?

You can request a quote for DihydroCsA directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for DihydroCsA?

Yes, KEHONG BIO provides custom synthesis services for DihydroCsA and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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