Thioflavin structure

Thioflavin

TL;DR: Thioflavin (CAS 5961-99-9) is a chemical compound with molecular formula C15H14S and molecular weight 226.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-phenyl-3,4-dihydro-2H-thiochromene

Also Known As: thioflavan, 2-phenyl-3,4-dihydro-2H-thiochromene, 2-PHENYLTHIOCHROMAN, NRYGFMAOIPXXBW-UHFFFAOYSA-, 2-phenyl-3,4-dihydro-2H-1-benzothiopyran

CAS: 5961-99-9
Molecular Formula C15H14S
Molecular Weight 226.08 g/mol
LogP 4.4
Topological Polar Surface Area 25.3 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 1
Exact Mass 226.08162
Heavy Atoms 16
Complexity 219.0

Chemical Identifiers

CAS Number 5961-99-9
SMILES C1CC2=CC=CC=C2SC1C3=CC=CC=C3
InChIKey NRYGFMAOIPXXBW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Analytical Reagents (2 patents) Biotechnology (5 patents) Heterocyclic Building Blocks (21 patents) Pharmaceutical Intermediates (19 patents)

Product Overview

Thioflavin (CAS 5961-99-9), with molecular formula C15H14S and molecular weight 226.08 g/mol. IUPAC: 2-phenyl-3,4-dihydro-2H-thiochromene.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Thioflavin

XLogP
4.4
TPSA (Topological Polar Surface Area)
25.3
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
1
Heavy Atoms
16
Complexity
219.0
Exact Mass
226.08162
Monoisotopic Mass
226.08162
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Thioflavin

The XLogP value of 4.4 indicates that Thioflavin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 25.3 Ų, Thioflavin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Thioflavin has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Thioflavin?

The CAS number of Thioflavin is 5961-99-9.

What is the molecular formula of Thioflavin?

The molecular formula of Thioflavin is C15H14S.

What is the molecular weight of Thioflavin?

The molecular weight of Thioflavin is 226.08 g/mol.

Where can I buy Thioflavin?

You can request a quote for Thioflavin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Thioflavin?

Yes, KEHONG BIO provides custom synthesis services for Thioflavin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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