4-Chloro-2-(4-methylphenyl)quinazoline
TL;DR: 4-Chloro-2-(4-methylphenyl)quinazoline (CAS 59490-96-9) is a chemical compound with molecular formula C15H11ClN2 and molecular weight 254.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-2-(4-methylphenyl)quinazoline
Also Known As: 4-chloro-2-(4-methylphenyl)quinazoline, 4-Chloro-2-(p-tolyl)quinazoline, 4-chloro-2-p-tolylquinazoline, 4-Chloro-2-(4-methylphenyl)-quinazoline, 4-Chloro-2-(4-chlorophenyl)-quinazoline
| Molecular Formula | C15H11ClN2 |
|---|---|
| Molecular Weight | 254.06 g/mol |
| LogP | 4.8 |
| Topological Polar Surface Area | 25.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 254.06108 |
| Heavy Atoms | 18 |
| Complexity | 276.0 |
Chemical Identifiers
| CAS Number | 59490-96-9 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=N2)Cl |
| InChIKey | KVEHRMVZMIBYCO-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
4-Chloro-2-(4-methylphenyl)quinazoline (CAS 59490-96-9), with molecular formula C15H11ClN2 and molecular weight 254.06 g/mol. IUPAC: 4-chloro-2-(4-methylphenyl)quinazoline.
Chemical Property Profile of 4-Chloro-2-(4-methylphenyl)quinazoline
Property Insights of 4-Chloro-2-(4-methylphenyl)quinazoline
The XLogP value of 4.8 indicates that 4-Chloro-2-(4-methylphenyl)quinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 25.8 Ų, 4-Chloro-2-(4-methylphenyl)quinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-2-(4-methylphenyl)quinazoline has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-2-(4-methylphenyl)quinazoline?
The CAS number of 4-Chloro-2-(4-methylphenyl)quinazoline is 59490-96-9.
What is the molecular formula of 4-Chloro-2-(4-methylphenyl)quinazoline?
The molecular formula of 4-Chloro-2-(4-methylphenyl)quinazoline is C15H11ClN2.
What is the molecular weight of 4-Chloro-2-(4-methylphenyl)quinazoline?
The molecular weight of 4-Chloro-2-(4-methylphenyl)quinazoline is 254.06 g/mol.
Where can I buy 4-Chloro-2-(4-methylphenyl)quinazoline?
You can request a quote for 4-Chloro-2-(4-methylphenyl)quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-2-(4-methylphenyl)quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-2-(4-methylphenyl)quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.