1'-Hydroxymidazolam
TL;DR: 1'-Hydroxymidazolam (CAS 59468-90-5) is a chemical compound with molecular formula C18H13ClFN3O and molecular weight 341.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methanol
Also Known As: 1-Hydroxymidazolam, 1'-hydroxymidazolam, alpha-Hydroxymidazolam, 1'-Hydroxy Midazolam, 1-Hydroxymethylmidazolam
| Molecular Formula | C18H13ClFN3O |
|---|---|
| Molecular Weight | 341.07 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 50.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 341.07312 |
| Heavy Atoms | 24 |
| Complexity | 491.0 |
Chemical Identifiers
| CAS Number | 59468-90-5 |
|---|---|
| SMILES | C1C2=CN=C(N2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4F)CO |
| InChIKey | QHSMEGADRFZVNE-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
1'-Hydroxymidazolam (CAS 59468-90-5), with molecular formula C18H13ClFN3O and molecular weight 341.07 g/mol. IUPAC: [8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methanol.
Chemical Property Profile of 1'-Hydroxymidazolam
Property Insights of 1'-Hydroxymidazolam
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1'-Hydroxymidazolam. With a topological polar surface area (TPSA) of 50.4 Ų, 1'-Hydroxymidazolam exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1'-Hydroxymidazolam has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1'-Hydroxymidazolam?
The CAS number of 1'-Hydroxymidazolam is 59468-90-5.
What is the molecular formula of 1'-Hydroxymidazolam?
The molecular formula of 1'-Hydroxymidazolam is C18H13ClFN3O.
What is the molecular weight of 1'-Hydroxymidazolam?
The molecular weight of 1'-Hydroxymidazolam is 341.07 g/mol.
Where can I buy 1'-Hydroxymidazolam?
You can request a quote for 1'-Hydroxymidazolam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1'-Hydroxymidazolam?
Yes, KEHONG BIO provides custom synthesis services for 1'-Hydroxymidazolam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.