Midazolam EP Impurity C
TL;DR: Midazolam EP Impurity C (CAS 59468-44-9) is a chemical compound with molecular formula C19H13ClFN3O2 and molecular weight 369.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid
Also Known As: Midazolam EP Impurity C, Midazolam BP Impurity B, Midazolam impurity C CRS, 8-chloro-6-(2-fluorophenyl)-1-methyl-4h-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, MIDAZOLAM IMPURITY C [EP IMPURITY]
| Molecular Formula | C19H13ClFN3O2 |
|---|---|
| Molecular Weight | 369.07 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 67.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 369.06802 |
| Heavy Atoms | 26 |
| Complexity | 589.0 |
Chemical Identifiers
| CAS Number | 59468-44-9 |
|---|---|
| SMILES | CC1=NC(=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F)C(=O)O |
| InChIKey | WZNYKINYEPCGAZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Midazolam EP Impurity C (CAS 59468-44-9), with molecular formula C19H13ClFN3O2 and molecular weight 369.07 g/mol. IUPAC: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid.
Chemical Property Profile of Midazolam EP Impurity C
Property Insights of Midazolam EP Impurity C
The XLogP value of 3.8 indicates that Midazolam EP Impurity C is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Midazolam EP Impurity C. Following Lipinski's Rule of Five, Midazolam EP Impurity C has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Midazolam EP Impurity C?
The CAS number of Midazolam EP Impurity C is 59468-44-9.
What is the molecular formula of Midazolam EP Impurity C?
The molecular formula of Midazolam EP Impurity C is C19H13ClFN3O2.
What is the molecular weight of Midazolam EP Impurity C?
The molecular weight of Midazolam EP Impurity C is 369.07 g/mol.
Where can I buy Midazolam EP Impurity C?
You can request a quote for Midazolam EP Impurity C directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Midazolam EP Impurity C?
Yes, KEHONG BIO provides custom synthesis services for Midazolam EP Impurity C and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.