Midazolam-D4 Maleate structure

Midazolam-D4 Maleate

TL;DR: Midazolam-D4 Maleate (CAS 59467-94-6) is a chemical compound with molecular formula C22H17ClFN3O4 and molecular weight 441.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

but-2-enedioic acid;8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine

Also Known As: Midazolam maleate, Midazolam-D4 Maleate, Midazolam-d4 maleate - 100 mg/mL in methanol, 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine maleate salt, (Z)-but-2-enedioic acid;8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine

CAS: 59467-94-6
Molecular Formula C22H17ClFN3O4
Molecular Weight 441.09 g/mol
LogP 4.04
Topological Polar Surface Area 105.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 7
Rotatable Bonds 3
Exact Mass 441.08917
Heavy Atoms 31
Complexity 590.0

Chemical Identifiers

CAS Number 59467-94-6
SMILES CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F.C(=CC(=O)O)C(=O)O
InChIKey XYGVIBXOJOOCFR-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Heterocyclic Building Blocks (50 patents) Pharmaceutical Intermediates (61 patents)

Product Overview

Midazolam-D4 Maleate (CAS 59467-94-6), with molecular formula C22H17ClFN3O4 and molecular weight 441.09 g/mol. IUPAC: but-2-enedioic acid;8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Midazolam-D4 Maleate

XLogP
4.04
TPSA (Topological Polar Surface Area)
105.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
7
Rotatable Bonds
3
Heavy Atoms
31
Complexity
590.0
Exact Mass
441.08917
Monoisotopic Mass
441.08917
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Midazolam-D4 Maleate

The XLogP value of 4.04 indicates that Midazolam-D4 Maleate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 105.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Midazolam-D4 Maleate. Following Lipinski's Rule of Five, Midazolam-D4 Maleate has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Midazolam-D4 Maleate?

The CAS number of Midazolam-D4 Maleate is 59467-94-6.

What is the molecular formula of Midazolam-D4 Maleate?

The molecular formula of Midazolam-D4 Maleate is C22H17ClFN3O4.

What is the molecular weight of Midazolam-D4 Maleate?

The molecular weight of Midazolam-D4 Maleate is 441.09 g/mol.

Where can I buy Midazolam-D4 Maleate?

You can request a quote for Midazolam-D4 Maleate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Midazolam-D4 Maleate?

Yes, KEHONG BIO provides custom synthesis services for Midazolam-D4 Maleate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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