氯马唑仑
TL;DR: 氯马唑仑 (CAS 59467-77-5) is a chemical compound with molecular formula C18H13Cl2N3 and molecular weight 341.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
氯马唑仑
8-chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
Also Known As: Climazolam, Climazolamum, Climasol, Climazolam [INN], Climazolamum [Latin]
| Molecular Formula | C18H13Cl2N3 |
|---|---|
| Molecular Weight | 341.05 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 30.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 341.04865 |
| Heavy Atoms | 23 |
| Complexity | 469.0 |
Chemical Identifiers
| CAS Number | 59467-77-5 |
|---|---|
| SMILES | CC1=NC=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl |
| InChIKey | CHCISLOJADQUNQ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
氯马唑仑 (CAS 59467-77-5), with molecular formula C18H13Cl2N3 and molecular weight 341.05 g/mol. IUPAC: 8-chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine.
Chemical Property Profile of 氯马唑仑
Property Insights of 氯马唑仑
The XLogP value of 3.0 indicates that 氯马唑仑 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.2 Ų, 氯马唑仑 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 氯马唑仑 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 氯马唑仑?
The CAS number of 氯马唑仑 is 59467-77-5.
What is the molecular formula of 氯马唑仑?
The molecular formula of 氯马唑仑 is C18H13Cl2N3.
What is the molecular weight of 氯马唑仑?
The molecular weight of 氯马唑仑 is 341.05 g/mol.
Where can I buy 氯马唑仑?
You can request a quote for 氯马唑仑 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 氯马唑仑?
Yes, KEHONG BIO provides custom synthesis services for 氯马唑仑 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.