4-Chloro-2-(thiophen-2-yl)quinazoline
TL;DR: 4-Chloro-2-(thiophen-2-yl)quinazoline (CAS 59455-95-7) is a chemical compound with molecular formula C12H7ClN2S and molecular weight 246.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-2-thiophen-2-ylquinazoline
Also Known As: 4-chloro-2-(thiophen-2-yl)quinazoline, 4-chloro-2-thien-2-ylquinazoline, 4-chloro-2-thiophen-2-ylquinazoline, N-Nitrosodiisobutylamine, 4-chloro-2-(2-thienyl)quinazoline
| Molecular Formula | C12H7ClN2S |
|---|---|
| Molecular Weight | 246.00 g/mol |
| LogP | 4.0117 |
| Topological Polar Surface Area | 25.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 246.00185 |
| Heavy Atoms | 16 |
| Complexity | 634.5687 |
Chemical Identifiers
| CAS Number | 59455-95-7 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=CS3)Cl |
Product Overview
4-Chloro-2-(thiophen-2-yl)quinazoline (CAS 59455-95-7), with molecular formula C12H7ClN2S and molecular weight 246.00 g/mol. IUPAC: 4-chloro-2-thiophen-2-ylquinazoline.
Chemical Property Profile of 4-Chloro-2-(thiophen-2-yl)quinazoline
Property Insights of 4-Chloro-2-(thiophen-2-yl)quinazoline
The XLogP value of 4.0117 indicates that 4-Chloro-2-(thiophen-2-yl)quinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 25.78 Ų, 4-Chloro-2-(thiophen-2-yl)quinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-2-(thiophen-2-yl)quinazoline has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-2-(thiophen-2-yl)quinazoline?
The CAS number of 4-Chloro-2-(thiophen-2-yl)quinazoline is 59455-95-7.
What is the molecular formula of 4-Chloro-2-(thiophen-2-yl)quinazoline?
The molecular formula of 4-Chloro-2-(thiophen-2-yl)quinazoline is C12H7ClN2S.
What is the molecular weight of 4-Chloro-2-(thiophen-2-yl)quinazoline?
The molecular weight of 4-Chloro-2-(thiophen-2-yl)quinazoline is 246.00 g/mol.
Where can I buy 4-Chloro-2-(thiophen-2-yl)quinazoline?
You can request a quote for 4-Chloro-2-(thiophen-2-yl)quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-2-(thiophen-2-yl)quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-2-(thiophen-2-yl)quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.