4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide
TL;DR: 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide (CAS 592467-05-5) is a chemical compound with molecular formula C18H14ClNO2S and molecular weight 343.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide
Also Known As: 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide, 4-chloro-N-(4-hydroxyphenyl)-N-[(thiophen-2-yl)methyl]benzamide, 4-chloro-N-(4-hydroxyphenyl)-N-(2-thienylmethyl)benzamide
| Molecular Formula | C18H14ClNO2S |
|---|---|
| Molecular Weight | 343.04 g/mol |
| LogP | 4.9541 |
| Topological Polar Surface Area | 40.54 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 343.04337 |
| Heavy Atoms | 23 |
| Complexity | 782.9036 |
Chemical Identifiers
| CAS Number | 592467-05-5 |
|---|---|
| SMILES | C1=CSC(=C1)CN(C2=CC=C(C=C2)O)C(=O)C3=CC=C(C=C3)Cl |
Product Overview
4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide (CAS 592467-05-5), with molecular formula C18H14ClNO2S and molecular weight 343.04 g/mol. IUPAC: 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide.
Chemical Property Profile of 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide
Property Insights of 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide
The XLogP value of 4.9541 indicates that 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.54 Ų, 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide?
The CAS number of 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide is 592467-05-5.
What is the molecular formula of 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide?
The molecular formula of 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide is C18H14ClNO2S.
What is the molecular weight of 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide?
The molecular weight of 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide is 343.04 g/mol.
Where can I buy 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide?
You can request a quote for 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide?
Yes, KEHONG BIO provides custom synthesis services for 4-chloro-N-(4-hydroxyphenyl)-N-(thiophen-2-ylmethyl)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.