奈利索尼
TL;DR: 奈利索尼 (CAS 59198-70-8) is a chemical compound with molecular formula C27H36F2O5 and molecular weight 478.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
奈利索尼
[2-(6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] pentanoate
Also Known As: Nerisona, diflucortolone valerate, [2-(6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] pentanoate
| Molecular Formula | C27H36F2O5 |
|---|---|
| Molecular Weight | 478.25 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 80.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 478.25308 |
| Heavy Atoms | 34 |
| Complexity | 943.0 |
Chemical Identifiers
| CAS Number | 59198-70-8 |
|---|---|
| SMILES | CCCCC(=O)OCC(=O)C1C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C |
| InChIKey | HHJIUUAMYGBVSD-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 15 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
奈利索尼 (CAS 59198-70-8), with molecular formula C27H36F2O5 and molecular weight 478.25 g/mol. IUPAC: [2-(6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl] pentanoate.
Chemical Property Profile of 奈利索尼
Property Insights of 奈利索尼
The XLogP value of 4.2 indicates that 奈利索尼 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 奈利索尼. Following Lipinski's Rule of Five, 奈利索尼 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 奈利索尼?
The CAS number of 奈利索尼 is 59198-70-8.
What is the molecular formula of 奈利索尼?
The molecular formula of 奈利索尼 is C27H36F2O5.
What is the molecular weight of 奈利索尼?
The molecular weight of 奈利索尼 is 478.25 g/mol.
Where can I buy 奈利索尼?
You can request a quote for 奈利索尼 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 奈利索尼?
Yes, KEHONG BIO provides custom synthesis services for 奈利索尼 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.