6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one
TL;DR: 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one (CAS 5900-48-1) is a chemical compound with molecular formula C15H13ClN2O2 and molecular weight 288.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one
Also Known As: 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one, 6-chloro-3,4-dihydro-4-hydroxy-3-methyl-4-phenyl-2(1H)-quinazolinone, 6-Chloro-4-hydroxy-3-methyl-4-phenyl-3,4-dihydroquinazolin-2(1H)-one
| Molecular Formula | C15H13ClN2O2 |
|---|---|
| Molecular Weight | 288.07 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 52.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 288.06656 |
| Heavy Atoms | 20 |
| Complexity | 386.0 |
Chemical Identifiers
| CAS Number | 5900-48-1 |
|---|---|
| SMILES | CN1C(=O)NC2=C(C1(C3=CC=CC=C3)O)C=C(C=C2)Cl |
| InChIKey | AWSGAAUIGPHERF-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one (CAS 5900-48-1), with molecular formula C15H13ClN2O2 and molecular weight 288.07 g/mol. IUPAC: 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one.
Chemical Property Profile of 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one
Property Insights of 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one. With a topological polar surface area (TPSA) of 52.6 Ų, 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one?
The CAS number of 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one is 5900-48-1.
What is the molecular formula of 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one?
The molecular formula of 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one is C15H13ClN2O2.
What is the molecular weight of 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one?
The molecular weight of 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one is 288.07 g/mol.
Where can I buy 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one?
You can request a quote for 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 6-chloro-4-hydroxy-3-methyl-4-phenyl-1H-quinazolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.