Cyclizine dihydrochloride
TL;DR: Cyclizine dihydrochloride (CAS 5897-18-7) is a chemical compound with molecular formula C18H24Cl2N2 and molecular weight 338.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-benzhydryl-4-methylpiperazine;dihydrochloride
Also Known As: Cyclizine 2HCl, Cyclizine dihydrochloride, Cyclizine hydrochloride, Marzine, Reis-fit
| Molecular Formula | C18H24Cl2N2 |
|---|---|
| Molecular Weight | 338.13 g/mol |
| LogP | 3.87 |
| Topological Polar Surface Area | 6.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 338.13165 |
| Heavy Atoms | 22 |
| Complexity | 253.0 |
Chemical Identifiers
| CAS Number | 5897-18-7 |
|---|---|
| SMILES | CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3.Cl.Cl |
| InChIKey | CKLJCUGYMOMAEJ-UHFFFAOYSA-N |
Product Overview
Cyclizine dihydrochloride (CAS 5897-18-7), with molecular formula C18H24Cl2N2 and molecular weight 338.13 g/mol. IUPAC: 1-benzhydryl-4-methylpiperazine;dihydrochloride.
Chemical Property Profile of Cyclizine dihydrochloride
Property Insights of Cyclizine dihydrochloride
The XLogP value of 3.87 indicates that Cyclizine dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Cyclizine dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Cyclizine dihydrochloride has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cyclizine dihydrochloride?
The CAS number of Cyclizine dihydrochloride is 5897-18-7.
What is the molecular formula of Cyclizine dihydrochloride?
The molecular formula of Cyclizine dihydrochloride is C18H24Cl2N2.
What is the molecular weight of Cyclizine dihydrochloride?
The molecular weight of Cyclizine dihydrochloride is 338.13 g/mol.
Where can I buy Cyclizine dihydrochloride?
You can request a quote for Cyclizine dihydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cyclizine dihydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Cyclizine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.