![(E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide structure](/static/products/5878/587845-77-0.webp)
(E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide
TL;DR: (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide (CAS 587845-77-0) is a chemical compound with molecular formula C19H16ClN3OS and molecular weight 369.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide
Also Known As: (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide, (2E)-N-[5-(4-chlorobenzyl)-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide, (E)-N-[5-(4-CHLOROBENZYL)-1,3,4-THIADIAZOL-2-YL]-2-METHYL-3-PHENYL-2-PROPENAMIDE, (2E)-N-{5-[(4-chlorophenyl)methyl](1,3,4-thiadiazol-2-yl)}-2-methyl-3-phenylpr op-2-enamide
| Molecular Formula | C19H16ClN3OS |
|---|---|
| Molecular Weight | 369.07 g/mol |
| LogP | 4.8243 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 369.07025 |
| Heavy Atoms | 25 |
| Complexity | 888.54736 |
Chemical Identifiers
| CAS Number | 587845-77-0 |
|---|---|
| SMILES | C/C(=C\C1=CC=CC=C1)/C(=O)NC2=NN=C(S2)CC3=CC=C(C=C3)Cl |
Product Overview
(E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide (CAS 587845-77-0), with molecular formula C19H16ClN3OS and molecular weight 369.07 g/mol. IUPAC: (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide.
Chemical Property Profile of (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide
Property Insights of (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide
The XLogP value of 4.8243 indicates that (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide?
The CAS number of (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide is 587845-77-0.
What is the molecular formula of (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide?
The molecular formula of (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide is C19H16ClN3OS.
What is the molecular weight of (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide?
The molecular weight of (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide is 369.07 g/mol.
Where can I buy (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide?
You can request a quote for (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-[5-[(4-chlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-methyl-3-phenylprop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.