2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one
TL;DR: 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one (CAS 5876-60-8) is a chemical compound with molecular formula C20H14ClNO3S and molecular weight 383.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-2-(3-chloro-1-benzothiophen-2-yl)-4-[(4-ethoxyphenyl)methylidene]-1,3-oxazol-5-one
Also Known As: 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one, (4E)-2-(3-chloro-1-benzothiophen-2-yl)-4-[(4-ethoxyphenyl)methylidene]-1,3-oxazol-5-one
| Molecular Formula | C20H14ClNO3S |
|---|---|
| Molecular Weight | 383.04 g/mol |
| LogP | 5.2979 |
| Topological Polar Surface Area | 47.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 383.0383 |
| Heavy Atoms | 26 |
| Complexity | 1050.6085 |
Chemical Identifiers
| CAS Number | 5876-60-8 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)/C=C/2\C(=O)OC(=N2)C3=C(C4=CC=CC=C4S3)Cl |
Product Overview
2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one (CAS 5876-60-8), with molecular formula C20H14ClNO3S and molecular weight 383.04 g/mol. IUPAC: (4E)-2-(3-chloro-1-benzothiophen-2-yl)-4-[(4-ethoxyphenyl)methylidene]-1,3-oxazol-5-one.
Chemical Property Profile of 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one
Property Insights of 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one
The XLogP value of 5.2979 indicates that 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.89 Ų, 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one?
The CAS number of 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one is 5876-60-8.
What is the molecular formula of 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one?
The molecular formula of 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one is C20H14ClNO3S.
What is the molecular weight of 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one?
The molecular weight of 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one is 383.04 g/mol.
Where can I buy 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one?
You can request a quote for 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(3-chloro-1-benzothien-2-yl)-4-(4-ethoxybenzylidene)-1,3-oxazol-5(4H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.