mefloquine
TL;DR: mefloquine (CAS 58737-31-8) is a chemical compound with molecular formula C17H16F6N2O and molecular weight 378.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2S)-piperidin-2-yl]methanol
Also Known As: mefloquine, Lariam, (+)-Threo-Mefloquine, (+)-anti-Mefloquine, Mefloquine Impurity 7
| Molecular Formula | C17H16F6N2O |
|---|---|
| Molecular Weight | 378.12 g/mol |
| LogP | 4.4479 |
| Topological Polar Surface Area | 45.15 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.11667 |
| Heavy Atoms | 26 |
| Complexity | 796.1653 |
Chemical Identifiers
| CAS Number | 58737-31-8 |
|---|---|
| SMILES | C1CCN[C@@H](C1)[C@H](C2=CC(=NC3=C2C=CC=C3C(F)(F)F)C(F)(F)F)O |
Product Overview
mefloquine (CAS 58737-31-8), with molecular formula C17H16F6N2O and molecular weight 378.12 g/mol. IUPAC: (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2S)-piperidin-2-yl]methanol.
Chemical Property Profile of mefloquine
Property Insights of mefloquine
The XLogP value of 4.4479 indicates that mefloquine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.15 Ų, mefloquine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, mefloquine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of mefloquine?
The CAS number of mefloquine is 58737-31-8.
What is the molecular formula of mefloquine?
The molecular formula of mefloquine is C17H16F6N2O.
What is the molecular weight of mefloquine?
The molecular weight of mefloquine is 378.12 g/mol.
Where can I buy mefloquine?
You can request a quote for mefloquine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for mefloquine?
Yes, KEHONG BIO provides custom synthesis services for mefloquine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.